Enturia

The Economic Impact of Surgical Site Infections (SSIs)

SSI is a common complication

Individuals contract 500,000 to 780,000 surgical site infections (SSIs) in the United States annually.^1,2 SSIs are one of the most common complications that a surgeon encounters, with an infection occurring after one of 780,000 operations in the United States annually.²

SSI-related costs

• SSIs result in at least 3.7 million additional days of hospitalization and cost $1.6 billion in hospital charges annually in the United States¹
• A systematic review of published evidence revealed the mean cost of treating each SSI case is $25,546 (range $1,783 to $134,602)³

ChloraPrep reduces microorganisms that can cause SSIs

ChloraPrep, a combination of 2% chlorhexidine gluconate (CHG) and 70% isopropyl alcohol (IPA), helps improve clinical patient outcomes by reducing the skin-dwelling microorganisms that can cause SSIs. The applicator eliminates hand-to-patient contact, helping prevent cross contamination. Together, the formulation and applicator provide a proven system that supports infection control guidelines for reducing incidences of SSIs.

ChloraPrep advantages

• Rapid acting: The 70% isopropyl alcohol in ChloraPrep rapidly kills microorganisms versus free iodine, which requires two minutes to begin antimicrobial activity⁵
• Persistent: ChloraPrep maintains antimicrobial activity for at least 48 hours^4,7 compared to two hours for free iodine⁵
• Broad spectrum: ChloraPrep antimicrobial activity is effective against microorganisms including gram-positive and gram-negative bacteria, Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant Enterococci (VRE), Clostridium difficile, Acineobacter, and most viruses and fungi^5,6,7
• Active in protein-rich biomaterials: Remains active in the presence of blood, serum, and other protein-rich biomaterials^6,8 unlike traditional iodophors, which are neutralized¹⁰
• Low irritation: CHG demonstrates low incidence of irritation⁶

Clinical studies support use of ChloraPrep and CHG formulations

According to a clinical study comparing ChloraPrep with two surgical preparation solutions — DuraPrep™ and Techni-Care® — ChloraPrep was the most efficacious for eliminating bacteria from hallux and toe sites (P<0.0001)⁹

Review other clinical studies and evidence-based guidelines supporting use of ChloraPrep and chlorhexidine-based formulations for patient preoperative skin preparation.

DuraPrep is a trademark of 3M Health Care; Techni-Care is a registered trademark of Care-Tech Laboratories, Inc.

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