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ChloraPrep Patient Preoperative Skin Preparation

The Economic Impact of Healthcare-associated Infections (HAIs)


HAI costs increase 26% over a 12-year period

According to the Centers for Disease Control and Prevention (CDC), 1.7 million people per year acquire an HAI, which results in 99,000 deaths — the equivalent of 271 people each day.1 HAIs in the United States were estimated to cost $4.5 billion in 1995.2 A more recent estimate puts HAI economic impact at more than $17 billion a year.3 The cost of treating HAIs will no longer be covered by Medicare as of October 2008, placing an increased economic burden on hospitals.

And, voluntary and mandatory reporting of HAIs is a rising trend. Voluntary hospital participation in the National Nosocomial Infections Surveillance (NNIS) System has increased from 60 hospitals at inception to about 300 in 2005.4 Seven states have enacted legislation mandating hospitals to report HAIs; six of those states require public disclosure of HAI data.5


The economic impact of bloodstream infections (BSIs) and surgical site infections (SSIs)

ChloraPrep reduces microorganisms that can cause BSIs and SSIs

ChloraPrep, a combination of 2% chlorhexidine gluconate (CHG) and 70% isopropyl alcohol (IPA), helps improve clinical patient outcomes by reducing the skin-dwelling microorganisms that can cause BSIs and SSIs. The applicator eliminates hand-to-patient contact, helping prevent cross contamination. Together, the formulation and applicator provide a proven system that supports infection control guidelines for reducing incidences of BSIs and SSIs.


ChloraPrep advantages

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1 Centers of Disease Control and Prevention. Estimates on HealthCare Associated Infections. Available at: http://www.cdc.gov/ncidod/dhqp/hai.html; Accessed October 2007.

2 Weinstein RA. Nosocomial infection update. Emerg Infect Dis. 4 1998:416-420.

3 Bhutta A, Gilliam C, Honeycutt M, et al. Reduction of bloodstream infections associated with catheters in paediatric intensive care unit: stepwise approach. BMJ. 334 2007:362-365.

4 Centers for Disease Control and Prevention (CDC) National Nosocomial Infectious Surveillance (NNIS) System. (2005) Overview, Last Updated February 16, 2005; Available at: http://www.cdc.gov/ncidod/dhqp/nnis.html; Accessed September 22, 2007.

5 Cardo D. CDC's Role in Monitoring and Preventing Healthcare-associated Infections, March 29, 2006, Testimony before The United States House of Representatives Committee on Energy and Commerce, Subcommittee on Oversight and Investigations. 2006; Available at: http://www.hhs.gov/asl/testify/t060329.html; Accessed September 22, 2006.

6 Stone PW, Braccia D, Larson E. Systematic review of economic analyses of healthcare-associated infections. Am J Infect Control. 33 2005:501-509.

7 Garcia R, Mulberry G, Brady A, Hibbard JS. Comparison of ChloraPrep and Betadine as preoperative skin preparation antiseptics. Poster presented at: 40th Annual Meeting of the Infectious Disease Society of America; October 25, 2002.

8 Crosby CT , Mares AK. Skin antisepsis: past, present, and future. J Vasc Access Devices. Spring 2001:26-31.

9 Denton GW. Chlorhexidine. In: Block SS. Disinfection, Sterilization, and Preservation. 5th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2001:321-336.

10 Data on file; Enturia.

11 Chaiyakunapruk N, Veenstra DL, Lipsky BA, Saint S. Chlorhexidine compared with povidone-iodine solution for vascular cather-site care: a meta-analysis. Ann Intern Med. 2002; 136: 792-801.

12 Gottardi W. Iodine and Iodine Compounds. In: Block SS. Disinfection, Serilization, and Preservation. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2001:159-183.

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