Enturia

The Economic Impact of Bloodstream Infections (BSIs)

The majority of BSIs are catheter related

The majority of BSIs are catheter-related bloodstream infections (CRBSIs). Individuals contract 250,000 CRBSIs each year in the United States according to the Centers for Disease Control and Prevention.¹ CRBSIs often originate in emergency rooms and intensive-care units, where 5.3 bloodstream infections occur per 1,000 days of central venous catheter insertion.²

CRBSI costs

• Catheter-related bloodstream infections (CRBSIs) as a whole cost 6.25 billion per year¹
  • Central-line associated bloodstream infections alone cost $2.3 billion annually¹
  • The mean cost of treating CRBSIs is $36,441 (range $1,822 to $107,156)³
• Patients with CRBSIs stay in the ICU an extra 20 days, and in the hospital an extra 22 days. This results in $70,000 increased ICU costs and more than $56,000 increased hospital costs⁴

ChloraPrep reduces microorganisms that can cause BSIs

ChloraPrep, a combination of 2% chlorhexidine gluconate (CHG) and 70% isopropyl alcohol (IPA), helps improve clinical patient outcomes by reducing the skin-dwelling microorganisms that can cause BSIs. The applicator eliminates hand-to-patient contact, helping prevent cross contamination. Together, the formulation and applicator provide a proven system that supports infection control guidelines for reducing incidences of BSIs.

ChloraPrep advantages

• Rapid acting: The 70% isopropyl alcohol in ChloraPrep rapidly kills microorganisms versus free iodine, which requires two minutes to begin antimicrobial activity⁵
• Persistent: ChloraPrep maintains antimicrobial activity for at least 48 hours^6,7 compared to two hours for free iodine⁵
• Broad spectrum: ChloraPrep antimicrobial activity is effective against microorganisms including gram-positive and gram-negative bacteria, Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant Enterococci (VRE), Clostridium difficile, Acineobacter, and most viruses and fungi^5,7,8
• Active in protein-rich biomaterials: Remains active in the presence of blood, serum, and other protein-rich biomaterials^8,9 unlike traditional iodophors, which are neutralized⁹
• Low irritation: CHG demonstrates low incidence of irritation⁸

Clinical study supports use of ChloraPrep

• According to one clinical study, the 2% chlorhexidine in ChloraPrep can help reduce the incidence of CRBSIs by 50%⁹
• Review more than 30 clinical studies and evidence-based guidelines supporting use of ChloraPrep and other 2% chlorhexidine and chlorhexidine-based formulations for preoperative skin preparation

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